関連する実験動画

Updated: May 12, 2026

Peering at Brain Polysomes with Atomic Force Microscopy
08:49

Peering at Brain Polysomes with Atomic Force Microscopy

Published on: March 16, 2016

メソフィル性ユーバクテリアの大きなリボソームサブユニットの高解像度構造

J Harms1, F Schluenzen, R Zarivach

  • 1Max-Planck-Research Unit for Ribosomal Structure, Notkestrasse 85, 22603, Hamburg, Germany.

Cell
|December 6, 2001
PubMed
まとめ

研究者は,Deinococcus radioduransの大型リボソームサブユニット (D50S) の高解像度構造を決定しました. この構造は,他のリボソームサブユニットとの主要な違いを明らかにし,タンパク質生物合成のダイナミクスに関する洞察を提供します.

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Ribosomal RNA Synthesis02:53

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Ribosome synthesis is a highly complex and coordinated process involving more than 200 assembly factors. The synthesis and processing of ribosomal components occurs not only in the nucleolus but also in the nucleoplasm and the cytoplasm of eukaryotic cells.
Ribosome biogenesis begins with the synthesis of 5S and 45S pre-rRNAs by distinct RNA polymerases. The primary transcripts are extensively processed and modified before they are bound and folded by ribosomal proteins and assembly factors,...
Ribosomes01:27

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Ribosomes translate genetic information encoded by messenger RNA (mRNA) into proteins. Both prokaryotic and eukaryotic cells have ribosomes. Cells that synthesize large quantities of protein—such as secretory cells in the human pancreas—can contain millions of ribosomes.
Ribosome Structure and Assembly
Ribosomes are composed of ribosomal RNA (rRNA) and proteins. In eukaryotes, rRNA is transcribed from genes in the nucleolus—a part of the nucleus that specializes in ribosome production. Within...
Ribosomes01:27

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Ribosomes translate genetic information encoded by messenger RNA (mRNA) into proteins. Both prokaryotic and eukaryotic cells have ribosomes. Cells that synthesize large quantities of protein—such as secretory cells in the human pancreas—can contain millions of ribosomes.
Ribosome Structure and Assembly
Ribosomes are composed of ribosomal RNA (rRNA) and proteins. In eukaryotes, rRNA is transcribed from genes in the nucleolus—a part of the nucleus that specializes in ribosome production. Within...