肺動脈シストリック圧の臨床相関値と基準間隔は,エコーカルジオグラフィ的に正常な被験者の間で測定された
B M McQuillan1, M H Picard, M Leavitt
1Cardiac Ultrasound, Massachusetts General Hospital, 55 Fruit St, Boston, Massachusetts, USA.
Circulation
|December 6, 2001
まとめ
肺動脈収縮圧 (PASP) は,正常な成人の年齢,BMI,性別によって影響を受けます. これらの要因は,特に高齢者または肥満者の場合,PASPの正確な正常範囲を確立するために決定的です.
科学分野:
- 心臓病学 心臓病学
- エコーカルディオグラフィー エコーカルディオグラフィー
- 肺動脈高血圧 肺動脈高血圧 肺動脈高血圧 肺動脈高血圧 肺動脈高血圧
背景:
- 健康な個体における肺動脈シストリック圧力 (PASP) に影響する要因に関するデータは限られている.
- 大規模な臨床エコーカルディオグラフィのデータベースを使用して,正常な被験者を特定しました.
研究 の 目的:
- 肺動脈シストリック圧力 (PASP) の相関値を正常な集団で測定する.
- ドップラートランストロラシックエコーカルディオグラフィ (Doppler transthoracic echocardiography,TTE) を使用してPASPの基準範囲を確立する.
主な方法:
- 102,818人の患者のデータベースから,正常なドップラーTTE試験を受けた15596人の患者の分析.
- 修正されたベルヌーリ方程式を用いたPASP計算で,右心房圧が10mmHgであると仮定する.
- PASP分析のための正常なTTEを持つ3790人の被験者の特定.
主要な成果:
- 正常な被験者の平均PASPは28.3+/-4.9mmHg (範囲15-57mmHg) でした.
- PASPは独立して年齢,BMI,男性性別,左心室後壁の厚さ,射出分数 (P<0.001) と関連していました.
- リスクが低い被験者におけるPASPの上限95%は37.2mmHgであり,28%はPASP>30mmHgであった.
結論:
- エコーカルジオグラフィ的に正常な被験者のPASPは,年齢,BMI,性別,壁の厚さ,射出分数と関連しています.
- 予想されるPASPの上限値は,高齢者または肥満者の場合,40mmHgまで上昇する可能性があります.
- 通常のPASP範囲を確立するために,年齢とBMIで修正された値が推奨されます.
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