まとめ
薬物乱用者の間で肝炎はよく見られる. 以前に過小評価されていた非親経薬物乱用は,肝臓酵素と肝炎の上昇の高頻度を示し,公衆衛生上の重大な懸念を示唆しています.
科学分野:
- 肝臓病理学 肝臓病理学
- 感染症 感染症は感染症です.
- 公衆衛生は公衆衛生である.
背景:
- 親体薬物乱用は,肝臓疾患の既知の危険因子です.
- 非親経中毒者における肝疾患の罹患率と影響は,まだ十分に研究されていない.
- 薬物乱用の流行は,重要で認識されていない健康上の影響を及ぼす可能性があります.
研究 の 目的:
- 薬物乱用歴のある若い軍人における肝機能障害の発生率を調査する.
- 親腸内薬物乱用者と非親腸内薬物乱用者の間の肝機能検査異常を比較するために.
- 非親体薬物使用者における肝炎の罹患率を決定する.
主な方法:
- 肝機能検査 (血清グルタミン酸酸化酸トランスアミナーゼ - SGOT) は,500人の若い軍人に実施されました.
- 患者は,親体経路による薬物乱用と非親体経路による薬物乱用の歴史に基づいて分類されました.
- 肝臓のバイオプシは,肝臓の病理性を評価するために,患者のサブセットで実施されました.
主要な成果:
- 非正常なSGOTレベルは,親体内薬物乱用者の66%,非親体内薬物乱用者の41%で観察されました.
- 肝臓生検は34人の患者のウイルス性または非特異性肝炎を明らかにした.
- 肝炎は,ゆっくりと回復するプロセスであるように見えました.
結論:
- 非親経薬物乱用は,肝臓酵素値上昇と肝炎の高い発生率と関連しています.
- 肝炎は,非親経薬物乱用の一般的な,以前に認識されていない合併症である可能性があります.
- これらの発見は,非親経薬物使用者の肝疾患に対する認識とスクリーニングの必要性を強調しています.
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