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Updated: Jul 13, 2026

The use of SC1 (Pluripotin) to Support mESC Self-renewal in the Absence of LIF
05:58

The use of SC1 (Pluripotin) to Support mESC Self-renewal in the Absence of LIF

Published on: November 18, 2009

JAK-STATの活性化によって指定された幹細胞の自己更新は,サポート細胞のシグナルに反応する

A A Kiger1, D L Jones, C Schulz

  • 1Department of Developmental Biology, Stanford University School of Medicine, Stanford, CA 94305-5329, USA.

Science (New York, N.Y.)
|December 26, 2001
PubMed
まとめ

ドロソフィラ胞の幹細胞は,自己再生のためにアピカルハブ細胞に依存しています. これらのハブ細胞は,アンペアド (Upd) リガンド経由で信号を送り,ジャヌスキナーゼ信号トランスデューサーと転写活性化器 (JAK-STAT) 経路を活性化させ,生殖幹細胞群を維持します.

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