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Updated: Jun 23, 2026

Use of a Hanging Weight System for Coronary Artery Occlusion in Mice
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アドレノメドゥリンは,内生性ペプチドであり,心血管損傷を食い止める

Tatsuo Shimosawa1, Yugo Shibagaki, Kotaro Ishibashi

  • 1Department of Nephrology and Endocrinology, Faculty of Medicine, the University of Tokyo, Bunkyo-ku, Tokyo, Japan.

Circulation
|January 5, 2002
PubMed
まとめ

内生性アドレノメドウリン (AM) は,酸化ストレスを抑制することにより,心血管損傷から保護します. AM(+/-) マウスを用いた研究では,アンジオテンシンIIと高塩分ダイエットで治療したときに,心血管損傷と酸化ストレスマーカーの増加が明らかになりました.

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