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Updated: May 3, 2026

Using RNA-interference to Investigate the Innate Immune Response in Mouse Macrophages
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MIFは,Toll型受容体4を調節することによって,先天的な免疫反応を調節する

T Roger1, J David, M P Glauser

  • 1Division of Infectious Diseases, Department of Internal Medicine, Centre Hospitalier Universitaire Vaudois, rue du Bugnon 46, CH-1011 Lausanne, Switzerland.

Nature
|January 10, 2002
PubMed
まとめ

マクロファージの移動阻害因子 (MIF) は,細菌とエンドトキシンに対するマクロファージの反応を調節し,先天的免疫に不可欠です. MIF欠乏症は,トール型受容体4 (TLR4) のダウンレギュレーションによってこれらの反応を損なう.

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