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Updated: Jun 25, 2026

A Restriction Enzyme Based Cloning Method to Assess the In vitro Replication Capacity of HIV-1 Subtype C Gag-MJ4 Chimeric Viruses
14:23

A Restriction Enzyme Based Cloning Method to Assess the In vitro Replication Capacity of HIV-1 Subtype C Gag-MJ4 Chimeric Viruses

Published on: August 31, 2014

複製能力のないアデノウイルスワクチンベクターは,効果的な抗免疫不全ウイルス免疫を誘発する

John W Shiver1, Tong-Ming Fu, Ling Chen

  • 1Merck Research Laboratories, West Point, Pennsylvania 19486, USA.

Nature
|January 18, 2002
PubMed
まとめ

複製不適格性アデノウイルス5型 (Ad5) ベクトルは,サルにおける類人猿免疫不全ウイルス (SIV) に対する細胞免疫反応を効果的に誘発した. Ad5ベクトルは,単独またはブースターとして,挑戦後に有意なウイルスの衰弱を示し,HIV-1ワクチンの開発に希望を示しています.

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