サルコメアタンパク質遺伝子変異は,高齢者の高縮性心筋病変症に起因する

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Updated: Jun 23, 2026

An Approach to Study Shape-Dependent Transcriptomics at a Single Cell Level
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An Approach to Study Shape-Dependent Transcriptomics at a Single Cell Level

Published on: November 2, 2020

Hideshi Niimura1, Kristen K Patton, William J McKenna

  • 1Howard Hughes Medical Institute and Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.

Circulation
|January 30, 2002
PubMed
まとめ

高齢者発症の高縮性心筋病変は遺伝的であり,サルコメアタンパク質の変異によって引き起こされる可能性があります. ミオシン結合タンパク質CとトロポニンIの特定の遺伝子変異は,早期発症の家族性疾患と異なるこの遅発症形態と関連しています.

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