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Updated: May 5, 2026

Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes
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Published on: September 27, 2013

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Th1特異の細胞表面タンパク質であるTim-3は,マクロファージの活性化と自己免疫疾患の重症度を調節する

Laurent Monney1, Catherine A Sabatos, Jason L Gaglia

  • 1Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.

Nature
|February 2, 2002
PubMed
まとめ

研究者らは,Th1細胞に新しい表面分子であるTim-3を特定した. Tim-3をブロックすると,実験的な自己免疫性脳髄炎が悪化し,Tim-3が自己免疫疾患における免疫反応とマクロファージの活性化を調節することを示唆しています.

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