進行性心不全の医療管理について
Anju Nohria1, Eldrin Lewis, Lynne Warner Stevenson
1Cardiovascular Division, Brigham and Women's Hospital, 75 Francis St, Tower 3-A, Boston, MA 02115, USA.
JAMA
|February 7, 2002
まとめ
現在進行性心不全の管理は,臨床試験ではなく,コンセンサスに基づいています. 既存の治療法を最適化し,新しい治療法を探求することは,より良い患者の治療結果と再入院を減らすために不可欠です.
科学分野:
- 心臓病学 心臓病学
- 内科内科は,内科の内科である.
- 薬理学 薬理学とは
背景:
- 先進的な心不全は,罹病率と死亡率に大きく寄与する.
- それは,効果的な治療法にもかかわらず,持続的な制限症状によって特徴付けられています.
研究 の 目的:
- 進行性心不全に対する現在の治療法をレビューする.
- 先進的な心不全管理における体系的な調査のための分野を特定する.
主な方法:
- MEDLINE,EMBASE,ベストエビデンス,エビデンスベースの医学,コクラン図書館 (1980-2001) の包括的な文献検索.
- ランダム化比較試験 (≥150患者) とその他の関連する臨床データを含む.
- ピアレビューされた出版物またはプロフェッショナル協会のガイドラインによって評価されたデータ品質.
主要な成果:
- マネジメントは,高圧の灌圧を特定し,治療することに焦点を当てています.
- アンジオテンシン変換酵素阻害剤とベータアドレナジック剤は進行を遅らせますが,定位化に問題があります.
- 調整された医療療法と心不全管理プログラムは,再入院を減らす;生存率は,症状の重症度によって著しく異なります.
結論:
- 現在進行性心不全の管理は,主にコンセンサスに基づいています.
- 新しい治療法に関する体系的な調査と,既存の治療法の最適化が必要である.
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