アルコール摂取と認知症のリスク:ロッテルダム研究
Annemieke Ruitenberg1, John C van Swieten, Jacqueline C M Witteman
1Department of Epidemiology and Biostatistics, Erasmus Medical Centre, PO Box 1738, 3000 DR Rotterdam, Netherlands.
Lancet (London, England)
|February 7, 2002
まとめ
軽度から中等度のアルコール摂取は,認知症のリスクを軽減する可能性があります. この研究では,毎日1〜3個のアルコール飲料を飲むことが,高齢者の認知症の発症のリスクが著しく低下するとの関連があることが判明しました.
科学分野:
- 神経学 神経学とは
- エピデミオロジー エピデミオロジー
- ゲロントロジーはゲロントロジーの学科です.
背景:
- 軽度から中等度のアルコールの摂取は,心血管疾患と脳血管疾患のリスクを低下させるものと関連しています.
- 血管疾患は,認知障害と認知症の危険因子として知られています.
研究 の 目的:
- アルコールの消費と認知症を発症するリスクとの関連を調査する.
- アルコールの摂取が高齢者の認知症リスクに影響するかどうかを調べる.
主な方法:
- 予期的な人口ベースのロッテルダム研究で,5395人の55歳以上の参加者が参加し,発症初期に認知症はなかった.
- 1999年までフォローアップされ,データは99.7%完全でした.
- 主要な人口統計的および健康的要因に調整された比例的な危険性回帰分析.
主要な成果:
- 軽度から中等度の飲酒 (1〜3杯/日) は,あらゆる原因による認知症 (HR 0.58) と血管性認知症 (HR 0.29) のリスクの低下と有意に関連していました.
- 重度の飲酒と有意な関連性は見つかりませんでした.
- アルコール飲料の種類は,観察された関係を変化させなかった.
結論:
- 軽度から中等度のアルコール摂取は,55歳以上で認知症のリスクが低いと関連しています.
- これらの発見は,高齢者集団における認知健康に対する適度なアルコール摂取の潜在的な保護効果を示唆しています.
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