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Updated: May 5, 2026

Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities
07:23

Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities

Published on: July 29, 2014

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オピオイド受容体密輸とモルヒン耐性の規制は,受容体オリゴメリゼーションによるものです

Li He1, Jamie Fong, Mark von Zastrow

  • 1Ernest Gallo Clinic and Research Center, University of California San Francisco, Emeryville, CA 94608, USA.

Cell
|February 8, 2002
PubMed
まとめ

慢性疼痛管理における課題であるモルヒン耐性を減らすことができます. モルヒネとDAMGOを併用すると,ミュオピオイド受容体 (MOR) の内細胞化が促進され,ネズミの鎮痛剤耐性が著しく低下します.

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