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Predrag Petrovic1, Eija Kalso, Karl Magnus Petersson

  • 1Cognitive Neurophysiology Research Group, Department of Clinical Neuroscience, Karolinska Institute, Stockholm 171 76, Sweden., Pain Clinic, Department of Anaesthesia and Intensive Care Medicine, Helsinki University Hospital, Finland.

Science (New York, N.Y.)
|February 9, 2002
PubMed
まとめ

プラセボとオピオイドの鎮痛剤は,似たような脳のメカニズムを共有しています. どちらもロストラル前帯状皮質 (rACC) を活性化し,脳幹の接続を伴うため,痛み調節のための共通の神経経路を示唆しています.

関連する概念動画

Analgesia and Pain Management01:25

Analgesia and Pain Management

Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...