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Updated: Jun 24, 2026

Large-scale Production of Recombinant RNAs on a Circular Scaffold Using a Viroid-derived System in Escherichia coli
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Published on: November 30, 2018

1ビーズ/1ストックソリューションプラットフォームを使用して,ビアリルを含むミディアムリングの多様性指向の合成

David R Spring1, Shyam Krishnan, Helen E Blackwell

  • 1Department of Chemistry and Chemical Biology, Howard Hughes Medical Institute, Institute of Chemistry and Cell Biology, Harvard University, Cambridge, Massachusetts 02138, USA.

Journal of the American Chemical Society
|February 14, 2002
PubMed
まとめ

この研究は,ビーズのオーガノキュプラート酸化を用いて,多様で複雑な小分子を合成するための新しい方法を開発した. この化学遺伝学のアプローチは,大規模な化合物ライブラリを通じて,生物学的経路の効率的な探索を可能にします.

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