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オゾンにさらされた運動する子供の喘息:コホート研究
Rob McConnell1, Kiros Berhane, Frank Gilliland
1Department of Preventive Medicine, University of Southern California School of Medicine, Los Angeles, CA 90089-9011, USA. mcconne@hsc.usc.edu
Lancet (London, England)
|February 15, 2002
まとめ
小児性喘息のリスクは,オゾン濃度が高い地域でのチームスポーツで増加します. 屋外での運動と大気汚染,特にオゾン汚染は,子供における新しい喘息診断に寄与する可能性があります.
科学分野:
- 環境衛生 環境衛生 環境衛生
- 小児呼吸器医学について
- エピデミオロジー エピデミオロジー
背景:
- 運動中の大気汚染の曝露が子供の喘息発症に与える影響は十分に理解されていません.
- この研究では,チームスポーツの参加,屋外での時間,および異なるレベルの大気汚染物質に曝露した子供の新規発症の喘息との関連を調査しています.
研究 の 目的:
- チームスポーツ,アウトドア活動,および子供の喘息発生率との関連を調べる.
- 空気汚染物質の濃度が運動と喘息の発症の関係を変化させるかどうかを判断する.
主な方法:
- 前発性喘息のない3535人の子どもを,南カリフォルニアの12のコミュニティで最大5年間追跡した.
- 喘息のリスクは,チームスポーツの参加と,オゾンやその他の汚染物質の濃度が高く,低かった地域で屋外で過ごした時間に基づいて評価されました.
- フォローアップ期間中に265件の新しい喘息診断が記録されました.
主要な成果:
- オゾン濃度が高い地域で3つ以上のスポーツをしている子どもは,非参加者と比較して,喘息を発症するリスクが3.3倍も高かった.
- オゾン濃度が低い地域では,スポーツ参加が喘息リスクに有意な影響を及ぼさないことが観察されました.
- 屋外で過ごす時間の増加は,高オゾンゾーンでは高い喘息発生率と関連していたが,低オゾンゾーンではそうではなかった.
- オゾン以外の汚染物質は,チームスポーツが喘息発症に与える影響に影響を与えなかった.
結論:
- チームスポーツなどの激しい運動と組み合わせた高濃度のオゾン濃度は,小児性喘息の発生率の増加と関連しています.
- 大気汚染と屋外運動は,小児集団における喘息の発症に寄与する要因である可能性があります.
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