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Updated: Jun 29, 2026

Reverse Yeast Two-hybrid System to Identify Mammalian Nuclear Receptor Residues that Interact with Ligands and/or Antagonists
10:51

Reverse Yeast Two-hybrid System to Identify Mammalian Nuclear Receptor Residues that Interact with Ligands and/or Antagonists

Published on: November 16, 2013

PPARalphaによる核共圧剤の対抗体媒介による徴用のための構造的基礎

H Eric Xu1, Thomas B Stanley, Valerie G Montana

  • 1Nuclear Receptor Discovery Research, GlaxoSmithKline, Research Triangle Park, NC 27709, USA. ex11957@gsk.com

Nature
|February 15, 2002
PubMed
まとめ

核受容体は,共抑制剤を介して遺伝子転写を抑制する. この研究は,核受容体-共抑制体複合体の結晶構造を明らかにし,遺伝子抑制のための保存されたメカニズムを明らかにします.

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