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Updated: Jul 20, 2026

Imaging Spatial Reorganization of a MAPK Signaling Pathway Using the Tobacco Transient Expression System
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MAPKK独立のp38alphaの活性化は,p38alphaのTAB1依存の自己リン酸化によって媒介されます

Baoxue Ge1, Hermann Gram, Franco Di Padova

  • 1Department of Immunology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

Science (New York, N.Y.)
|February 16, 2002
PubMed
まとめ

ミトゲン活性化タンパク質キナーゼ (MAPK) は,典型的なキナーゼカスケードとは独立して活性化することができる. TAB1タンパク質との相互作用は,p38alpha MAPKの自己リン酸化と活性化を誘発し,代替信号伝達経路を示唆する.

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