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Updated: Oct 2, 2026

Regioselective O-Glycosylation of Nucleosides via the Temporary 2',3'-Diol Protection by a Boronic Ester for the Synthesis of Disaccharide Nucleosides
08:46

Regioselective O-Glycosylation of Nucleosides via the Temporary 2',3'-Diol Protection by a Boronic Ester for the Synthesis of Disaccharide Nucleosides

Published on: July 26, 2018

プラナー・キラル・ヌクレオフィールによって触媒化されたベータ・ラクタムのエナチオセレクティブ・スタウディンガー合成

Brian L Hodous1, Gregory C Fu

  • 1Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.

Journal of the American Chemical Society
|February 21, 2002
PubMed
まとめ

この研究は,スタウディンガー反応のための新しい平面-キラル触媒を導入し,β-ラクトームの効率的でステレオ選択的合成を可能にします. このブレークスルーは,価値ある医薬品の中間製品を作るための新しい経路を提供します.

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