Stat3βの特定のアブレーションは,Stat3反応性遺伝子発現のパターンを歪め,エンド毒性ショックからの回復を妨げます

Joo-Yeon Yoo1, David L Huso, Daniel Nathans

  • 1Department of Molecular Biology and Genetics, Howard Hughes Medical Institute, Baltimore, MD, USA.

Cell
|February 21, 2002
PubMed
まとめ

タンパク質の同型であるStat3βは,全身性炎症の制御に不可欠です. Stat3betaを欠いたマウスは,内毒性ショックからの回復が低下し,免疫応答におけるその役割を強調した.

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