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Updated: May 2, 2026

Examination of Thymic Positive and Negative Selection by Flow Cytometry
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BH3-only Bcl-2ファミリーのメンバーであるBimは,自己反応性チモサイトのアポトーシスに必要なものです

Philippe Bouillet1, Jared F Purton, Dale I Godfrey

  • 1The Walter and Eliza Hall Institute of Medical Research, Melbourne, P.O. The Royal Melbourne Hospital, Victoria 3050, Australia.

Nature
|February 23, 2002
PubMed
まとめ

プロアポプトシスタンパク質Bimは,発達中の自己反応性Tリンパ球の除去に不可欠である. その欠如は,チモサイトアポトシスを防止し,自己免疫疾患の予防におけるその役割を強調します.

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