レリッシュの活性化とドロソフィラの抗菌免疫反応におけるペプチドグリカン認識タンパク質 (PGRP) の必要性

Kwang-Min Choe1, Thomas Werner, Svenja Stöven

  • 1Molecular Biology Program, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA.

Science (New York, N.Y.)
|March 2, 2002
PubMed
まとめ

微生物の細胞壁の成分は,先天的免疫を活性化する. ペプチドグリカン認識タンパク質PGRP-LCは,NF-kappaBシグナル伝達を制御することによって,ドロソフィラの抗菌ペプチド遺伝子誘導に不可欠です.

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