長期にわたり大麻を大量に摂取し,治療を求める大麻使用者の認知機能
Nadia Solowij1, Robert S Stephens, Roger A Roffman
1National Drug and Alcohol Research Centre, University of New South Wales, Sydney, NSW 2052, Australia. n.solowij@unsw.edu.au
JAMA
|March 7, 2002
まとめ
長期にわたる大麻使用は,記憶と注意力を著しく低下させ,使用年数が増えるにつれて欠陥が悪化します. これらの認知障害は,禁欲の期間を経ても持続します.
科学分野:
- 神経科学は神経科学である.
- 心理学 心理学とは
背景:
- 認知機能障害は長期にわたる大麻使用と関連していますが,特定の要因や欠陥の持続性は不明です.
- これらの影響を理解することは,大麻依存症の治療を求める個人にとって非常に重要です.
研究 の 目的:
- 大麻の使用期間が,大麻依存症の治療を受けている個人の特定の認知機能にどのように影響するか調査する.
- 長期使用者,短期使用者,非使用者の認知能力を区別する.
主な方法:
- マルチサイト・レトロスペクティブ・クロスセクション研究で,ほぼ毎日大麻を使用している102人と,使用していない33人の対照群が参加した.
- 神経心理学的テストは,中位17時間の禁酒期間を経て,注意,記憶,および実行機能の評価を行った.
- 参加者は長期 (平均23.9年) と短期 (平均10.2年) の大麻使用グループに分けられた.
主要な成果:
- 長期的な大麻使用者は,短期間の使用者とコントロールと比較して,記憶と注意のパフォーマンスを著しく低下させました.
- 学習,記憶,復習における特定の欠陥は,長期使用者の間で観察されました.
- 両方の使用者グループは,時間の見積もりの障害を示し,パフォーマンスはしばしば大麻の使用期間と相関していました.
結論:
- 長期にわたり大麻を大量に摂取すると,記憶力や注意力の持続的な障害が生じます.
- これらの認知欠陥は,定期的な大麻使用の期間が長くなるにつれて悪化し,中毒状態を超えて持続します.
- 研究結果は,長期にわたる大麻消費が認知健康に与える持続的な影響を強調しています.
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