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関連する概念動画

What are Proteins?01:55

What are Proteins?

Overview
Antibody Structure01:10

Antibody Structure

Overview
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...
Protein and Protein Structure02:15

Protein and Protein Structure

Proteins are one of the most abundant organic molecules in living systems and have the most diverse range of functions of all macromolecules. Proteins may be structural, regulatory, contractile, or protective. They may serve in transport, storage, or membranes; or they may be toxins or enzymes. Their structures, like their functions, vary greatly. They are all, however, amino acid polymers arranged in a linear sequence.
A protein's shape is critical to its function. For example, an enzyme can...
Conjugated Proteins02:50

Conjugated Proteins

Simple proteins and protein complexes contain only amino acids. In contrast, many other proteins, called conjugated proteins, covalently bond with non-protein moieties.
Nucleoproteins are protein complexes that contain nucleic acids, categorized as deoxyribonucleoproteins (DNPs) or ribonucleoproteins (RNPs) respectively. The nucleosome is a typical example of a DNP where nuclear DNA is associated with histone proteins. The major antigen for the Covid-19 virus SARS-CoV is an RNP that is critical...
Antibody Structure01:10

Antibody Structure

Overview
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...
Antibody Structure and Classes01:25

Antibody Structure and Classes

Antibodies, also known as immunoglobulins, are produced by B cells in response to foreign substances, such as bacteria and viruses. These proteins are critical for recognizing and neutralizing these substances, protecting the body from potential harm.
The basic structure of an antibody consists of four protein chains: two identical heavy chains and two identical light chains. These chains are held together by disulfide bonds and other non-covalent interactions, forming a Y-shaped structure.

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関連する実験動画

Updated: Jul 5, 2026

Stability and Structure of Bat Major Histocompatibility Complex Class I with Heterologous β2-Microglobulin
11:17

Stability and Structure of Bat Major Histocompatibility Complex Class I with Heterologous β2-Microglobulin

Published on: March 10, 2021

類の胃質:濃度と分子形態

E Straus, R S Yalow, H Gainer

    Science (New York, N.Y.)
    |November 14, 1975
    PubMed
    まとめ

    哺乳類に含まれるガストリンというホルモンは,海や陸にも存在する. その存在と濃度は,軟体動物と哺乳類のガストリンとの構造的類似性を示唆しています.

    科学分野:

    • 比較生理学 比較生理学について
    • エンドクリノロジー エンドクリノロジー
    • マリン・バイオロジーの海洋生物学

    背景:

    • ガストリンは,哺乳類の胃腸機能を調節する重要なホルモンです.
    • 以前の研究は,主に脊椎動物のシステム内のガストリンに焦点を当てていました.

    研究 の 目的:

    • 軟体動物種におけるガストリンの存在と特性を調査する.
    • 軟骨動物と哺乳類の胃膜の構造的同質性を探求する.

    主な方法:

    • 血液および胃腸組織におけるガストリンの免疫ヒストキミカル分析.
    • 豚のガストリン標準を用いたガストリン濃度の定量化.

    主要な成果:

    • 免疫反応性ガストリンは,海 (Aplysia californica) と陸 (Otala lactea) の中で異質な形態で検出されました.
    • これらの軟体動物における血中のガストリンの濃度は,豚,人間,犬などの哺乳類で観察された濃度と同等であった.

    結論:

    • 哺乳類のガストリンと構造的に類似しているので,進化的に保存されていることを示している.
    • この研究は,脊椎動物を超えてガストリンの存在に関する私たちの理解を広げ,より広範な生物学的役割を示唆しています.

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    Mechanical Separation and Protein Solubilization of the Outer and Inner Perivitelline Sublayers from Hen's Eggs
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    Mechanical Separation and Protein Solubilization of the Outer and Inner Perivitelline Sublayers from Hen's Eggs

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    Covalent Labeling with Diethylpyrocarbonate for Studying Protein Higher-Order Structure by Mass Spectrometry
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    Covalent Labeling with Diethylpyrocarbonate for Studying Protein Higher-Order Structure by Mass Spectrometry

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    関連する実験動画

    Last Updated: Jul 5, 2026

    Stability and Structure of Bat Major Histocompatibility Complex Class I with Heterologous β2-Microglobulin
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    Stability and Structure of Bat Major Histocompatibility Complex Class I with Heterologous β2-Microglobulin

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    06:12

    Mechanical Separation and Protein Solubilization of the Outer and Inner Perivitelline Sublayers from Hen's Eggs

    Published on: January 27, 2021

    Covalent Labeling with Diethylpyrocarbonate for Studying Protein Higher-Order Structure by Mass Spectrometry
    10:36

    Covalent Labeling with Diethylpyrocarbonate for Studying Protein Higher-Order Structure by Mass Spectrometry

    Published on: June 15, 2021