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Updated: May 12, 2026

Isolation and Kv Channel Recordings in Murine Atrial and Ventricular Cardiomyocytes
11:33

Isolation and Kv Channel Recordings in Murine Atrial and Ventricular Cardiomyocytes

Published on: March 12, 2013

ブルガダ症候群と長QT症候群の両方のフェノタイプを引き起こすNa(+) チャンネル変異:メカニズムのシミュレーション研究

Colleen E Clancy1, Yoram Rudy

  • 1Cardiac Bioelectricity Research and Training Center, Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio 44106-7207, USA.

Circulation
|March 13, 2002
PubMed
まとめ

心臓のNa(+) チャンネル変異 (1795insD) は逆説的に長いQTとブルガダ症候群を引き起こす. 計算モデルによると,この突然変異は心臓細胞に差異的に影響を及ぼし,さまざまな臨床結果を説明しています.

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