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Updated: May 28, 2026

Improved Preparation and Preservation of Hippocampal Mouse Slices for a Very Stable and Reproducible Recording of Long-term Potentiation
09:39

Improved Preparation and Preservation of Hippocampal Mouse Slices for a Very Stable and Reproducible Recording of Long-term Potentiation

Published on: June 26, 2013

構成的に活性なCREBタンパク質の発現は,シナプス捕獲を強化することによって,長期的な増強の遅い段階を促進します

Angel Barco1, Juan M Alarcon, Eric R Kandel

  • 1Center for Neurobiology and Behavior, College of Physicians and Surgeons of Columbia University, 1051 Riverside Drive, New York, NY 10032, USA.

Cell
|March 15, 2002
PubMed
まとめ

マウスの海馬部ニューロンにおける構成的に活性なCREBは,転写に独立して長期的な増強 (LTP) を促進する. これは,LTP捕獲のためのタンパク質プライムシナプスを示唆し,シナプス可塑性に関する洞察を提供している.

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