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シラプロリンがペプチド構成と生物活性に及ぼす影響

Florine Cavelier1, Bertrand Vivet, Jean Martinez

  • 1Laboratoire des Amino acides, Peptides et Protéines, UMR-CNRS 5810, Universités de Montpellier I et II, UM II, CC19-34095 Montpellier Cedex 05, France.

Journal of the American Chemical Society
|March 21, 2002
PubMed
まとめ

研究者は,プロリンアナログであるシラプロリン (Sip) を合成し,同様のペプチド構造と生物学的活性を維持していることを発見しました. この新しいプロリン代用品は,また,分解に対するペプチド耐性を高めます.

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