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Updated: Jul 24, 2026

Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides (CHIPS)
06:34

Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides (CHIPS)

Published on: June 20, 2014

bis ((フェノキシイミン) ベースのチタン触媒を用いたプロピレン挿入のメカニズム:グループIVの触媒システムにプロピレンの異常な二次挿入

Phillip D Hustad1, Jun Tian, Geoffrey W Coates

  • 1Department of Chemistry and Chemical Biology, Baker Laboratory, Cornell University, Ithaca, New York 14853-1301, USA.

Journal of the American Chemical Society
|April 4, 2002
PubMed
まとめ

この研究は,フェノキシイミンベースのチタン触媒を用いたプロピレン挿入におけるユニークな地域選択性を明らかにしています. これらの触媒は,ポリメリゼーションにおける新しい発見である2,1-地域化学を持つプロピレンを独占的に挿入します.

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All meta-directing substituents are deactivating groups. These substituents withdraw electrons from the aromatic ring, making the ring less reactive toward electrophilic substitution. For example, the nitration of nitrobenzene is 100,000 times slower than that of benzene because of the deactivating effect of the nitro group. The first step in an electrophilic aromatic substitution is the addition of an electrophile to form a resonance-stabilized carbocation. The energy diagrams for the...
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