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Updated: Feb 8, 2026

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酵素によるGTP水解:アビニシオ分子ダイナミクス研究からの洞察

Andrea Cavalli1, Paolo Carloni

  • 1Scuola Internazionale Superiore di Studi Avanzati, Istituto Nazionale di Fisica della Materia, Via Beirut 2-4, I-34014 Trieste, Italy.

Journal of the American Chemical Society
|April 4, 2002
PubMed
まとめ

Ab initio計算では,グアノシントリホスファートの水解機構を明らかにした. 触媒水は,ガンマリン酸に直接ではなく,Gln61に陽子を転送し,Cdc42/Cdc42GAP酵素処理を明らかにします.

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