H2AX

Arkady Celeste1, Simone Petersen, Peter J Romanienko

  • 1Experimental Immunology Branch, National Cancer Institute, NIH, Bethesda, MD 20892, USA.

Science (New York, N.Y.)
|April 6, 2002
PubMed
まとめ

ヒストンH2AXはDNA修復に不可欠です. H2AXが欠けているマウスは,放射線感受性,不妊症,およびDNA修復複合体の組み立ての障害を示し,ゲノムの安定性を維持する上で重要な役割を強調しています.

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