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一次性肺高血圧は,II型骨形態遺伝タンパク質受容体の肺血管表現の低下と関連しています

Carl Atkinson1, Susan Stewart, Paul D Upton

  • 1Department of Medicine, University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, Cambridge, UK.

Circulation
|April 10, 2002
PubMed
まとめ

肺における骨形態遺伝タンパク質II型受容体 (BMPR-II) 発現の低下は,肺高血圧に関連しています. この発見は,BMPR-IIが,この重症疾患の特徴である血管病変に作用することを示唆しています.

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