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Updated: Aug 11, 2026

Analyzing Protein Dynamics Using Hydrogen Exchange Mass Spectrometry
11:37

Analyzing Protein Dynamics Using Hydrogen Exchange Mass Spectrometry

Published on: November 29, 2013

大豆リポキシゲネーゼ-1における温度依存の同位体効果:タンパク質のダイナミクスと相関する水素トンネリング

Michael J Knapp1, Keith Rickert, Judith P Klinman

  • 1Department of Chemistry, University of California, Berkeley, California 94720, USA.

Journal of the American Chemical Society
|April 11, 2002
PubMed
まとめ

大豆リポキシゲナーゼ-1 (SLO) は,量子トンネリングを通じて水素原子の移転を容易にする. 変異は,活性サイト構造がこのトンネリングにどのように影響するかを明らかにし,いくつかの変異は再編成エネルギーを強化し,他の変異はゲートダイナミクスを変化させます.

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