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骨格筋におけるミトコンドリア生体生成の調節は,CaMKによって行われる

Hai Wu1, Shane B Kanatous, Frederick A Thurmond

  • 1Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Science (New York, N.Y.)
|April 16, 2002
PubMed
まとめ

耐久運動は,カルシウムシグナル伝達を通じて,筋肉のミトコンドリアを活性化させます. この研究では,カルシウム/カルモジュリン依存タンパク質キナーゼIV (CaMKIV) がPGC-1を活性化し,ミトコンドリア生体生成を強化し,筋肉の疲労を軽減することを示しています.

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