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Heart Valves01:16

Heart Valves

The human heart is a complex organ with an intricate system of valves that regulate blood flow. There are two main types of valves: atrioventricular (AV) valves and semilunar valves.
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...
Overview of Systemic Arteries01:11

Overview of Systemic Arteries

The human body is a complex, well-organized machine, and at the heart of its operations lies the circulatory system. This network of blood vessels, which includes systemic arteries, plays a vital role in maintaining life by transporting nutrients, oxygen, and waste products to and from cells throughout the body.
Systemic circulation is the part of the cardiovascular system that carries oxygenated blood away from the heart to the body's tissues and returns deoxygenated blood back to the heart.
Arteries of the Upper Limbs01:12

Arteries of the Upper Limbs

The subclavian artery transitions into the axillary artery as it exits the chest and enters the axillary region. This artery is critical for supplying blood to the shoulder area, including the head of the humerus, through the humeral circumflex arteries. As the vessel continues into the upper arm or brachium, it becomes the brachial artery. This artery plays a key role in vascularizing the brachial region and bifurcates at the elbow into several branches. These branches include the deep...
Arteries of Lower Limbs01:20

Arteries of Lower Limbs

The external iliac artery transitions out of the body cavity, entering the femoral region of the lower leg, and is renamed the femoral artery at the point where it traverses the body wall. This artery is responsible for the distribution of blood to the thigh's deep muscles and the skin's ventral and lateral regions, achieved through several minor branches and the lateral deep femoral artery, which also spawns a lateral circumflex artery. The knee area receives blood from the genicular artery,...
Veins of Upper Limbs01:17

Veins of Upper Limbs

The human circulatory system, a marvel of biological engineering, is a complex network of vessels that transport blood throughout the body. Among these, the veins responsible for carrying blood from the upper limbs are divided into two categories: deep and superficial.
The deep venous system is primarily composed of the ulnar and radial veins. The ulnar vein, which drains the fingers through the superficial palmar venous arches, and the radial vein, which serves the palms via the deep palmar...
Applications of Integration to Find Blood Flow01:27

Applications of Integration to Find Blood Flow

Blood flow through a cylindrical blood vessel can be mathematically described using the principles of laminar flow, a regime in which fluid moves smoothly in parallel layers. In this model, the velocity of the blood is not uniform across the cross-section of the vessel; rather, it varies with the radial distance from the center. The maximum velocity occurs along the central axis, decreasing progressively toward the vessel walls, where it reaches zero due to viscous drag.Approximating Blood...

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Updated: May 19, 2026

Functional Assessment of the Donor Heart During Ex Situ Perfusion: Insights from Pressure-Volume Loops and Surface Echocardiography
08:21

Functional Assessment of the Donor Heart During Ex Situ Perfusion: Insights from Pressure-Volume Loops and Surface Echocardiography

Published on: October 11, 2022

キネトコアにおける統合機能.

Soni L Shimoda1, Frank Solomon

  • 1Department of Biology and Center for Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Cell
|April 17, 2002
PubMed
まとめ
この要約は機械生成です。

キネトコアタンパク質は,触媒的および構造的機能を備えています. スピンドルの組み立てと染色体分離のタイミングと精度を統合しています.

さらに関連する動画

Continuous Venous-Arterial Doppler Ultrasound During a Preload Challenge
09:32

Continuous Venous-Arterial Doppler Ultrasound During a Preload Challenge

Published on: January 20, 2023

Point-of-Care Ultrasound for Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation Without Left Ventricular Venting
03:40

Point-of-Care Ultrasound for Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation Without Left Ventricular Venting

Published on: January 17, 2025

関連する実験動画

Last Updated: May 19, 2026

Functional Assessment of the Donor Heart During Ex Situ Perfusion: Insights from Pressure-Volume Loops and Surface Echocardiography
08:21

Functional Assessment of the Donor Heart During Ex Situ Perfusion: Insights from Pressure-Volume Loops and Surface Echocardiography

Published on: October 11, 2022

Continuous Venous-Arterial Doppler Ultrasound During a Preload Challenge
09:32

Continuous Venous-Arterial Doppler Ultrasound During a Preload Challenge

Published on: January 20, 2023

Point-of-Care Ultrasound for Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation Without Left Ventricular Venting
03:40

Point-of-Care Ultrasound for Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation Without Left Ventricular Venting

Published on: January 17, 2025

科学分野:

  • 細胞生物学 細胞生物学
  • 分子生物学は分子生物学である.
  • 遺伝学 遺伝学とは

背景:

  • キネトコア成分は,細胞分裂に不可欠です.
  • これらのタンパク質は染色体分離において役割を果たします.
  • 彼らの二重な機能は,ますます認識されています.

研究 の 目的:

  • キネトコアタンパク質の統合された役割を解明する.
  • これらのタンパク質がスパインドル形質変異にどのように影響するかを理解するために.
  • 染色体分離の精度とタイミングに及ぼす影響を調べる.

主な方法:

  • 触媒活性を決定する生化学的測定法.
  • スピンドルと染色体ダイナミクスを観察するための顕微鏡.
  • タンパク質の機能を研究するための遺伝子操作 in vivo.

主要な成果:

  • 主要なキネトコアタンパク質の触媒作用が実証されている.
  • スピンドル形質変異とキネトコア機能の統合を展示した.
  • 染色体分離のタイミングと精度を調節するための証拠を提供した.

結論:

  • キネトコアタンパク質は多機能で,構造的および触媒的な役割の両方を持っています.
  • これらのタンパク質は,スパインドル組立と染色体分離の調整に中心的です.
  • 正確な細胞分裂を確保するための新しい洞察.