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Updated: Jun 23, 2026

A Model of Disturbed Flow-Induced Atherosclerosis in Mouse Carotid Artery by Partial Ligation and a Simple Method of RNA Isolation from Carotid Endothelium
11:00

A Model of Disturbed Flow-Induced Atherosclerosis in Mouse Carotid Artery by Partial Ligation and a Simple Method of RNA Isolation from Carotid Endothelium

Published on: June 23, 2010

サイクロオキシゲネーゼ-2は,LDL受容体欠乏マウスの早期動脈硬化病変形成を促進する

Michael E Burleigh1, Vladimir R Babaev, John A Oates

  • 1Department of Pharmacology, Vanderbilt University Medical Center, Nashville, Tenn, USA.

Circulation
|April 17, 2002
PubMed
まとめ

選択的サイクロオキシゲナーゼ-2 (COX-2) 阻害は,マウスの早期動脈硬化症を減少させます. マクロファージのCOX-2発現は,動脈硬化症の発達にも寄与し,抗炎症戦略をサポートします.

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