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Updated: Jul 25, 2026

Development of a Backbone Cyclic Peptide Library as Potential Antiparasitic Therapeutics Using Microwave Irradiation
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Published on: January 26, 2016

7-N-(マーカプトアルキル) ミトミシン:薬物機能に対するサイクル化の影響

Younghwa Na1, Shuang Wang, Harold Kohn

  • 1Department of Chemistry, University of Houston, Houston, Texas 77204-5641, USA.

Journal of the American Chemical Society
|April 25, 2002
PubMed
まとめ

新しい方法により,ミトマイシンC (MMC) とポルフィロマイシン (PFC) のチオルを成功裏に合成し,特徴づけました. チオルの構造と安定性は,アルキルリンカーに依存し,より長いリンカーは,サイクリングまたはリング活性化ではなく,フリーチオルの形成を促進します.

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