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Updated: Jan 26, 2026

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タンパク質キナーゼCdeltaが欠けているマウスのB細胞の増殖と自己免疫が増加した

Akimoto Miyamoto1, Keiko Nakayama, Hiroyuki Imaki

  • 1Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka 812-8582, Japan.

Nature
|April 27, 2002
PubMed
まとめ

タンパク質キナーゼC-デルタ (PKC-デルタ) は通常,B細胞の増殖を抑制する. PKC-デルタが欠けているマウスは,制御不能なB細胞増殖を示し,免疫耐性を維持する上で重要な役割を果たしていることを示しています.

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