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Updated: May 5, 2026

Modified Yeast-Two-Hybrid System to Identify Proteins Interacting with the Growth Factor Progranulin
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グルタミン酸受容体相互作用タンパク質GRIP1は,キネシンをデンドライトに直接誘導する

Mitsutoshi Setou1, Dae-Hyung Seog, Yosuke Tanaka

  • 1Department of Cell Biology and Anatomy, Graduate School of Medicine, University of Tokyo, Hongo 7-3-1, Bunkyo-ku, Tokyo 113-0033, Japan.

Nature
|May 3, 2002
PubMed
まとめ

GluR2相互作用タンパク質 (GRIP1) は,直接キネシンモーターを誘導し,α-アミノ-3-ヒドロキシ-5-メチルイソクサゾール-4-プロピオネート (AMPA) 受容体をニューロン dendrites に誘導します. このタンパク質とモーターの相互作用が,神経機能にとって極めて重要な輸送方向を決定する.

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