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Updated: Jul 18, 2026

Real Time Monitoring of Intracellular Bile Acid Dynamics Using a Genetically Encoded FRET-based Bile Acid Sensor
09:21

Real Time Monitoring of Intracellular Bile Acid Dynamics Using a Genetically Encoded FRET-based Bile Acid Sensor

Published on: January 4, 2016

コレステロールを下げる天然製品で,FXRの対抗リガンドとしてコレステロールを下げる

Nancy L Urizar1, Amy B Liverman, D'Nette T Dodds

  • 1Department of Molecular and Cellular Biology, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX 77030, USA.

Science (New York, N.Y.)
|May 4, 2002
PubMed
まとめ

グーグルツリー (guggul tree) のグーグルステロンは,ファルネソイドX受容体 (FXR) を阻害することによって,LDLコレステロールを低下させます. この発見は,天然の化合物によるコレステロール低下のメカニズムを明らかにしています.

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