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Updated: Jul 17, 2026

Using Caenorhabditis elegans as a Model System to Study Protein Homeostasis in a Multicellular Organism
12:38

Using Caenorhabditis elegans as a Model System to Study Protein Homeostasis in a Multicellular Organism

Published on: December 18, 2013

タンパク質ネットワークのトポロジーの特異性と安定性

Sergei Maslov1, Kim Sneppen

  • 1Department of Physics, Brookhaven National Laboratory, Upton, NY 11973, USA. maslov@bnl.gov

Science (New York, N.Y.)
|May 4, 2002
PubMed
まとめ

タンパク質の相互作用と遺伝子調節を含む細胞分子ネットワークは,非ランダムな構造を示しています. この組織は,機能モジュール間のクロストークを抑制し,混乱に対する細胞の強さを高めます.

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Proteins are chains of amino acids linked together by peptide bonds. Upon synthesis, a protein folds into a three-dimensional conformation, critical to its biological function. Interactions between its constituent amino acids guide protein folding, and hence the protein structure is primarily dependent on its amino acid sequence.
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Protein Networks02:26

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An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
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