若い男性におけるシネコロナリア動脈撮影

C C Welch¹, W L Proudfit, F M Sones

¹Department of Clinical Cardiology, Department of Cardiovascular Disease and Cardiac Laboratory, Cleveland Clinic Foundation, Cleveland, Ohio, USA.

Circulation

|October 1, 1970

まとめ

冠動脈疾患は40歳未満の男性に多く見られ,約半数が著しい狭窄を示しています. コレステロールレベルは,冠動脈病変の存在と重症度と強く相関しています.

科学分野:

心臓病学心臓病学
血管医学血管医学とは
診断用イメージング

背景:

冠動脈疾患 (CAD) は通常,高齢者集団と関連しています.
胸痛を経験している若い人は,しばしばCADの診断評価を受けます.

研究の目的:

40歳未満の男性における冠動脈収縮の発生率と特徴を調査する.
血管検査結果と臨床症状,心電図 (ECG) 結果,コレステロール値の相関を図る.

主な方法:

胸の痛みを呈する40歳未満の男性723人にシネコロナリア動脈造影が行われました.
分析には,病変の分布,重度,心電図,左心室図,血清コレステロールとの相関が含まれていました.

主要な成果:

男性の49%は冠動脈の狭窄が顕著であった (≥50%).
前側下垂動脈が最も頻繁に影響を受け,右側冠動脈が最も完全な閉塞を示した.
高コレステロールレベル (>275 mg/100 ml) は,低コレステロールレベル (<200 mg/100 ml,20%) に比べて,CADの有意に高い罹患率 (81%) と関連していました.

結論:

胸の痛みに評価された若い男性では,重大な冠動脈収縮が一般的です.
コレステロールレベルは,この集団におけるCADリスクの重要な指標です.
血管検査の結果は,特に典型的なプレゼンテーションでは,臨床診断とよく相関しています.

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