関連する実験動画

Updated: May 3, 2026

Detecting the Ligand-binding Domain Dimerization Activity of Estrogen Receptor Alpha Using the Mammalian Two-Hybrid Assay
09:07

Detecting the Ligand-binding Domain Dimerization Activity of Estrogen Receptor Alpha Using the Mammalian Two-Hybrid Assay

Published on: December 19, 2018

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共通のエストロゲン受容体多型化は,ホルモン置換療法の効果をEセレクチンに増加させるが,C反応性タンパク質には影響しない

David M Herrington1, Timothy D Howard, K Bridget Brosnihan

  • 1Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27157-1045, USA. kklein@wfubmc.edu

Circulation
|May 9, 2002
PubMed
まとめ

エストロゲン受容体アルファ (ER-alpha) IVS1-401 C/C遺伝子型は,ホルモン置換療法 (HRT) のEセレクチン減少を増加させるが,C反応性タンパク質 (CRP) は減少しない. このポリモルフィズムはB-mybの結合部位を作り,エストロゲンの作用に影響を与えます.

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