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Updated: Jan 10, 2026

Reprograming Model of Human Monocyte-derived Macrophages for In-vitro Assays
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Published on: April 18, 2025

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誘導された Ets 抑制複合体は,末端マクロファージの分化中に成長停止を調節する

Günter W Klappacher1, Victoria V Lunyak, David B Sykes

  • 1Department of Cellular and Molecular Medicine, Howard Hughes Medical Institute, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.

Cell
|May 15, 2002
PubMed
まとめ

Ets抑制剤であるMETS/PE1は,細胞サイクル遺伝子を阻害することによって,マクロファージの分化中に細胞分裂を停止します. これは,永久的な細胞サイクル終了のためにDP103およびE2F/pRBタンパク質との相互作用を必要とする.

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