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Updated: Jul 6, 2026

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O結合シアリルオリゴサッカリドの効率的な化学酵素合成

Ola Blixt1, Kirk Allin, Laura Pereira

  • 1The Scripps Research Institute, Department of Molecular Biology, MEM-L71, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.

Journal of the American Chemical Society
|May 16, 2002
PubMed
まとめ

新しい化学酵素法により,重要ながんバイオマーカーであるシアライテッドTおよびTn抗原を効率的に合成します. このアプローチは,複合的なO結合グリカン (O-linked glycans) の準備的なスケール合成のために再結合シアリルトランスフェラスを利用します.

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