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Updated: Aug 11, 2026

Retropinacol/Cross-pinacol Coupling Reactions - A Catalytic Access to 1,2-Unsymmetrical Diols
10:12

Retropinacol/Cross-pinacol Coupling Reactions - A Catalytic Access to 1,2-Unsymmetrical Diols

Published on: April 4, 2014

(-) -ラウリマリドの非対称的全合成:非対称的なグリコラートアルキル化反応を利用する

Michael T Crimmins1, Matthew G Stanton, Shawn P Allwein

  • 1Department of Chemistry, Venable and Kenan Laboratories of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-3290, USA. crimmins@email.unc.edu

Journal of the American Chemical Society
|May 23, 2002
PubMed
まとめ

この研究は,抗腫瘍マクロリド (-) - ラウリマリドの簡潔な全合成を示しています. 主要な戦略には,非対称なグリコラートアルキレーションとダイアステレオ選択的結合が含まれ,一般的な異体化問題を成功裏に回避しました.

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