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Updated: May 4, 2026

Mechanism of Regulation of Adipocyte Numbers in Adult Organisms Through Differentiation and Apoptosis Homeostasis
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Mechanism of Regulation of Adipocyte Numbers in Adult Organisms Through Differentiation and Apoptosis Homeostasis

Published on: June 3, 2016

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PPARのガンマ2刺激によるアディポゲネシスには,トランスクリプションコアクティベーターTRAP220が必要です

Kai Ge1, Mohamed Guermah, Chao-Xing Yuan

  • 1Laboratory of Biochemistry and Molecular Biology, The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA.

Nature
|May 31, 2002
PubMed
まとめ

TRAP220タンパク質は,TRAP複合体内のPPARガンマ(2) -選択的共活性化剤として作用し,アディポゲネシスに不可欠です. 欠乏すると脂肪細胞の分化が妨げられるが,筋肉細胞の発達は妨げられない.

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