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Basics of Multivariate Analysis in Neuroimaging Data
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4つの一般的な医学雑誌の2つの変数間の相関のエキストラポレーション
1Department of Research, Jersey Shore Medical Center, Meridian Health System, 1945 State Rte 33, Neptune, NJ 07753, USA. yhkuo@jhu.edu
JAMA
|June 1, 2002
まとめ
医学文献におけるデータ抽出は一般的でリスクが高い. ある研究によると,分析された記事の59%は,明確な指示なしに抽出を用いており,誤った結論に至る可能性がある.
科学分野:
- 医学研究方法論 医学研究方法論
- 科学出版の基準について
背景:
- 統計的妥当性は,観測されたデータ範囲に限られています.
- 観測されたデータを超えて抽出すると,固有のリスクが伴う.
研究 の 目的:
- 著名な医学雑誌におけるデータエクストラポレーションの問題の頻度を評価する.
- 科学的出版物におけるエクストラポレーションに関するベストプラクティスの遵守を評価する.
主な方法:
- BMJ,JAMA,The Lancet,およびNEJM (2000年1月から6月まで) に掲載された論文のマニュアルレビュー.
- 含有基準:原始データとフィットされた回帰線を備えた分散図.
- エクストラポレーションの定義:観測データを超えて伸びるフィットライン.
主要な成果:
- 37件の論文が含有基準を満たし,22件 (59%) がエキストラポレーションを行った.
- 異なるラインタイプとのエクストラポレーションが示された記事は見つかりませんでした.
- 抽出されたプロットの11%は不合理な値を示し,8%は観察されたデータ以外の結論を導き出した.
結論:
- 医療用品の有意な割合は,適切な指示なしにエクストラポレーションを使用しています.
- 研究者,レビュー者,編集者は,エクストラポレーションリスクに対処し,軽減する必要があります.
- 正確な科学的報告を確保するために,意識と実践の改善が必要である.
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