関連する実験動画
Updated: Jul 20, 2026
14:20
Absolute Quantum Yield Measurement of Powder Samples
Published on: May 12, 2012
Jarzynski's equalityの実験的なテストにおける非均衡測定からの均衡情報
Jan Liphardt1, Sophie Dumont, Steven B Smith
1Department of Chemistry, Biophysics Graduate Group, University of California, Berkeley, CA 94720, USA.
Science (New York, N.Y.)
|June 8, 2002
まとめ
研究者らは,ジャージンスキーをテストした.
科学分野:
- 熱力学は熱力学である.
- 統計力学 統計力学とは
- 単一分子生物物理学について
背景:
- Jarzynskiの平等 (1997年) は,不可逆的な労働を,均衡の自由エネルギー差と結びつける.
- これにより,非均衡プロセスから均衡パラメータを導出することができます.
- 実験的熱力学における根本的な課題.
研究 の 目的:
- Jarzynskiの等式を実験的に検証するために.
- 均衡と非均衡のシステムの統計力学を橋渡しする.
- 単一分子操作データの熱力学分析を拡張する.
主な方法:
- 単一のRNA分子を機械的に伸ばす.
- 逆戻り可能なおよび不可逆的なストレッチプロトコルの両方を実行します.
- ジャージンスキの等式を不可逆的な作業軌道に適用する.
主要な成果:
- Jarzynski の等式は,自由エネルギー差 (DeltaG) を正確に回復しました.
- 結果は,リバーシブルストレッチによる平均作業のk(B) T/2以内でした.
- Jarzynskiの等式の最初の実験的実装とテスト.
結論:
- ジャージンスキーの等式は,均衡と非均衡の統計力学の間の橋渡しをします.
- 均衡状態を超えた単一分子実験の熱力学分析を可能にします.
- 理論的な予測を生体物理学的文脈で検証する.
関連する概念動画
02:46Uncertainty in Measurement: Reading Instruments
Counting is the type of measurement that is free from uncertainty, provided the number of objects being counted does not change during the process. Such measurements result in exact numbers. By counting the eggs in a carton, for instance, one can determine exactly how many eggs are there in the carton. Similarly, the numbers of defined quantities are also exact. For example, 1 foot is exactly 12 inches, 1 inch is exactly 2.54 centimeters, and 1 gram is exactly 0.001 kilograms. Quantities...
01:07Static Equilibrium - II
Static equilibrium is a special case in mechanics that is very important in everyday life. It occurs when the net force and the net torque on an object or system are both zero. This means that both the linear and angular accelerations are zero. Thus, the object is at rest, or its center of mass is moving at a constant velocity. However, this does not mean that no forces are acting on the object within the system. In fact, there are very few scenarios on Earth in which no forces are acting upon...
01:21Rigid Body Equilibrium Problems - II
A rigid body is in static equilibrium when the net force and the net torque acting on the system are equal to zero.
Consider two children sitting on a seesaw, which has negligible mass. The first child has a mass (m1) of 26 kg and sits at point A, which is 1.6 meters (r1) from the pivot point B; the second child has a mass (m2) of 32 kg and sits at point C. How far from the pivot point B should the second child sit (r2) to balance the seesaw?
Consider two children sitting on a seesaw, which has negligible mass. The first child has a mass (m1) of 26 kg and sits at point A, which is 1.6 meters (r1) from the pivot point B; the second child has a mass (m2) of 32 kg and sits at point C. How far from the pivot point B should the second child sit (r2) to balance the seesaw?
01:17Wald-Wolfowitz Runs Test II
The Wald-Wolfowitz runs test, commonly referred to as the runs test, is a nonparametric test used to assess the randomness of ordered data. The test evaluates the number of runs, which are consecutive sequences of similar elements within the data. If the number of runs is significantly higher or lower than expected, the data is considered non-random, indicating a detectable pattern or structure.
For binary data, runs are identified using symbols such as + and −, or equivalently, 1s and 0s. In...
For binary data, runs are identified using symbols such as + and −, or equivalently, 1s and 0s. In...
01:12Instrument Calibration
Instrument calibration is essential for ensuring that instruments produce accurate and consistent results. It is vital in manufacturing, healthcare, testing laboratories, and scientific research. Calibration processes are specific to each instrument and help enhance data accuracy. Each instrument has a unique calibration process tailored to its design and function to improve data accuracy.
Analytical Balance Calibration
An analytical balance measures mass and requires regular calibration to...
Analytical Balance Calibration
An analytical balance measures mass and requires regular calibration to...
01:23Measurement of Air Content in Concrete
Air content measurement in concrete is critical for ensuring structural integrity and durability of concrete structures, especially in environments prone to severe weather conditions. Accurate air content analysis optimizes concrete's resistance to freeze-thaw cycles and enhances its workability and strength. Several methods are standardized under ASTM guidelines to measure the air content in fresh concrete, each suitable for different concrete types and conditions.
The pressure method,...
The pressure method,...