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Updated: Jun 10, 2026
11:00
Determination of the Gas-phase Acidities of Oligopeptides
Published on: June 24, 2013
トライコーディネートからヘクサコーディネートに変換する. フォスフォラン-フォスファトラン系を形成する
Natalya V Timosheva1, A Chandrasekaran, Roberta O Day
1Department of Chemistry, University of Massachusetts, Amherst, Massachusetts 01003-9336, USA.
Journal of the American Chemical Society
|June 13, 2002
まとめ
この研究は,固体状態と溶液状態の間の3〜6座標構造から変換するリン化合物の最初の例を明らかにしています. これらの化合物は平衡状態で存在し,ダイナミックな協調化学を示しています.
科学分野:
- オーガノフォスファルス化学
- 協調化化学について
- 固体化学と溶液化学について
背景:
- 固体阻害アミンとのリン二塩化物の反応性を調べる.
- アミン置換剤を基にしたリン化合物の構造的多様性を探求する.
研究 の 目的:
- 新しいリン酸-アミン複合体を合成し,特徴づけること.
- 異なる状態におけるこれらの複合体の構造的変容と均衡を調査する.
- 反応経路に対するステリック阻害の影響を理解するために.
主な方法:
- 三協調フォスフォニートおよび六協調フォスフォラン-フォスファトラン複合体の合成.
- 固体構造の決定のためのX線結晶学.
- 変数温度 (31) P NMRスペクトロスコピーを用いた溶液状態分析.
主要な成果:
- 三協調のフォスフォニート (1) と六協調のフォスフォラン-フォスファトラン (2) の形成.
- (2) のX線構造は,ヒドロキシル基の酸化添加をリンに示す.
- 溶液の研究は,三座標と六座標の両方の酸化物種が平衡状態にあり,固体構造が優位であることを示しています.
結論:
- 固体から溶液への3〜6座標のリン酸化変換の最初の文書化事例です.
- 溶液の平衡状態に存在する異なったの幾何学の実証.
- ステリック保護の欠如で観察された水解反応は,フォスフィナート構造を生成します.
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