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Updated: Jul 21, 2026

Employing Digital Droplet PCR to Detect BRAF V600E Mutations in Formalin-fixed Paraffin-embedded Reference Standard Cell Lines
10:16

Employing Digital Droplet PCR to Detect BRAF V600E Mutations in Formalin-fixed Paraffin-embedded Reference Standard Cell Lines

Published on: October 8, 2015

人間の癌におけるBRAF遺伝子の変異

Helen Davies1, Graham R Bignell, Charles Cox

  • 1Cancer Genome Project, The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SA, UK.

Nature
|June 18, 2002
PubMed
まとめ

BRAF変異は,メラノーマや他のがんに多く見られます. これらのBRAF遺伝子変異は,キナーゼ活性を増大させ,がん細胞の成長を促し,メラノーマの新たな治療標的を示唆する.

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