アディポサイト由来プラズマタンパク質アディポネクチンは,血小板由来成長因子-BB結合タンパク質として作用し,血管の滑らかな筋肉細胞における成長因子誘発の共通後受容体信号を調節する

Yukio Arita1, Shinji Kihara, Noriyuki Ouchi

  • 1Department of Internal Medicine and Molecular Science, Graduate School of Medicine, Osaka University, Osaka and First Institute of New Drug Research, Otsuka Pharmaceutical Co, Ltd, Tokushima, Japan.

Circulation
|June 19, 2002
PubMed
まとめ

アディポネクチン (Adiponectin) はアディポサイトに由来するタンパク質で,人間の大動脈の滑らかな筋肉細胞の増殖と移動を抑制する. それは特にPDGF-BBに結合し,成長因子のシグナル伝達を調節し,血管の再構築における役割を示唆しています.

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